The Immediate release aaplacoat grades work in wide application range which includes tablet binding, taste masking, odor masking and providing protective coatings like moisture protection, film coating etc.

MOISTURE BARRIER, TASTE MASKING, FILM COATING

Taste and odor masking, light and moisture protection
* Swallowability improvement
* Soluble in gastric fluid up to pH 5.0
* Swellable and permeable above pH 5.0
* Low viscosity
* High pigment binding capacity
* Excellent adhesion
* High effectiveness in thin coatings

AAPLACOAT^® E 100- Granules
AAPLACOAT^® E 12,5- Organic solution
AAPLACOAT^® E PO- Powder
AAPLACOAT^® E PO- ReadyMix Powder

The delayed release aaplacoat grades eases gastrointestinal targeted drug release which helps formulator to have targeted drug delivery in like Jejenum (5.5 pH), Duodenum (6.0 pH) and Colon (7.0 pH).

* Easily combined to achieve a specific dissolution pH
* Highly stable, with rapid dissolution for precise targeting
* Well-defined characteristics to safeguard the gastric mucosa from aggressive actives
* Able to protect the transit of APIs sensitive to gastric fluid

Small Intestine: (ENTERIC COATING)

AAPLACOAT^® L 30 D-55: Aqueous dispersion soluble above pH 5.5
AAPLACOAT^® L 100-55: Powder soluble above pH 5.5
AAPLACOAT^® FL 30 D-55: NEW Aqueous dispersion soluble above pH 5.5
AAPLACOAT^® L 100: Powder soluble above pH 6.0
AAPLACOAT^® L 12,5: Organic solution soluble above pH 6.0
AAPLACOAT^® ERD: Aqueous dispersion

SUSTAINED RELEASE

Sustained release and controlled release aaplacoat grades designed to provide desired release profile throughout the gastrointestinal tract to increase the therapeutic effect. Different polymer combinations allow custom-tailored release profiles to achieve the desired drug delivery performance.


* Multiple combination options to control delivery throughout the GI tract
* Solutions for once-per-day dosing, pulsatile release and other custom profiles
* Insoluble with pH-independent permeability
* Flexible options for high or low permeability

AAPLACOAT^® RL PO- Powder
AAPLACOAT^® RL 100- Granules
AAPLACOAT^® RL 30 D- Aqueous dispersion
AAPLACOAT^® RL 12,5- Organic solution

* Insoluble, high permeability, pH-independent swelling
* Customized release profiles by combining with aaplacoat RS at different ratios

AAPLACOAT^® RS PO- Powder
AAPLACOAT^® RS 100- Granules
AAPLACOAT^® RS 30 D- Aqueous dispersion
AAPLACOAT^® RS 12,5- Organic solution

* Insoluble, low permeability, pH-independent swelling
*Customized release profiles by combining with aaplacoat RL at different ratios

AAPLACOAT^® NM 30 D - Aqueous dispersion

*Insoluble, low permeability, pH-independent swelling
*Highly flexible, suitable as matrix formers

SOLUBILITY AND BIOAVAILABILITY ENHANCEMEN

* Polymer, process technology and formulation solutions
* Specialized in solid dispersions, API and silica technologies
* Well-defined processing characteristics for spray drying and hot melt extrusion
* Robust thermoplastic properties
* Broad miscibility with APIs and excipients
* Down-streaming and further processing options
* Predictive systems to select lead carrier excipients and process parameters for trials

Colonic delivery: (SUSTAINED RELEASE)

AAPLACOAT^® S 100:         Powder -                     soluble above pH 7.0
AAPLACOAT^® S 12,5:       Organic solution -        soluble above pH 7.0
AAPLACOAT^® FS 30 D:     Aqueous dispersion -   soluble above pH 7.0
AAPLACOAT^® FS 100:       Powder -                      soluble above pH 7.0

AAPLACOAT series comprise of Methylarylic acid copolymers which is used in film coating, Enteric coating, sustain release, moisture barrier, taste masking, colon target, binders, matrix forming, trasndermal-therapeutic system etc, in all oral solid dosage forms including multi particulates, regular or matrix tablets, patches and hard or soft-gel capsules.